| 摘要: |
| 制备了氧化铟锡（ITO）/二氧化锡（SnO2）/二氧化钛（TiO2）/金纳米粒子（Au NPs）纳米复合电极（ITO/SnO2/TiO2/Au NPs），并利用它发展了可以选择性检测唾液酸（SA）的光电化学（PEC）法.采用旋涂法制备了ITO/SnO2电极，并通过静电纺丝和磁控溅射技术在ITO/SnO2表面原位合成了TiO2纳米纤维和Au NPs.与单纯SnO2比，ITO/SnO2/TiO2/Au NPs纳米复合电极的光电性能显著提高.这可能与Au NPs的局域表面等离子体共振效应（LSPR）和TiO2/SnO2异质结之间的协同作用密切相关.之后，通过金硫键（Au-S）将四巯基苯硼酸（4-MPBA）修饰在ITO/SnO2/TiO2/Au NPs电极表面，利用4-MPBA和SA之间的非特异性酯化反应，发展了可以特异性检测SA的PEC传感平台. |
| 关键词: 光电化学（PEC）法 纳米复合材料 葡萄糖氧化酶 唾液酸（SA） |
| DOI：10.3969/J.ISSN.1000-5137.2021.06.002 |
| 分类号:O657.1 |
| 基金项目:国家自然科学基金（21976122）；上海市晨光计划 |
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| The development of photoelectrochemical method for specific detection of sialic acid based on SnO2/TiO2/Au NPs |
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YAO Jingjing, YANG Yu, GU Xinxin, ZHONG Qi, YANG Haifeng, WU Yiping
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College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China
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| Abstract: |
| In this work, indium tin oxide(ITO)/tin oxide(SnO2)/titanium dioxide(TiO2)/gold nanoparticles(Au NPs) nanocomposite electrode(ITO/SnO2/TiO2/Au NPs) was prepared and used to develop a photoelectrochemical(PEC) method for the selective detection of sialic acid(SA). Firstly, ITO/SnO2 electrode was prepared by spin coating method, and then TiO2 nanofibers and Au NPs were synthesized on the surface of ITO/SnO2 by electrospinning and magnetron sputtering. Compared with pure SnO2, the photoelectric performance of ITO/SnO2/TiO2/Au NPs nanocomposite electrode is significantly improved. This may be closely related to the local plasmon resonance effect(LSPR) of Au NPs, and the synergistic effect between TiO2/SnO2 heterojunction. After that, 4-mercaptophenylboronic acid (4-MPBA) was modified on the surface of ITO/SnO2/TiO2/Au NPs electrode by Au-S bond, and a PEC sensing platform was developed to specifically detect SA by non-specific esterification reaction between 4-MPBA and SA. |
| Key words: photoelectrochemical (PEC) method nanocomposite materials glucose oxidase sialic acid(SA) |
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