| 摘要: |
| 共轭聚合物以其独特的结构和性能得到了广泛的关注.聚苯胺（PANI）纳米复合材料制备工艺简单、成本低廉、毒性低、易于功能化，从而在癌症治疗方面取得了巨大的进展.通过不同功能的化合物修饰制备的PANI纳米复合材料极大地拓宽了癌症治疗领域.基于PANI纳米复合材料，文章总结了其在癌症诊疗领域的光热治疗、协同治疗、多模态成像引导治疗和智能响应治疗的研究进展，并分析了其发展趋势. |
| 关键词: 聚苯胺（PANI）纳米复合材料 光热治疗 协同治疗 多模态成像 智能响应 |
| DOI：10.3969/J.ISSN.1000-5137.2021.06.009 |
| 分类号:O611.3 |
| 基金项目:国家自然科学基金重大研究计划培育项目（91959105） |
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| Progress in polyaniline nanocomposites for cancer diagnosis and treatment |
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ZHOU Xuesu1, CHENG Yuying1, YAN Ge1, TIAN Qiwei1,2, YANG Shiping1
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1.College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China;2.College of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai 200237, China
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| Abstract: |
| Conjugated polymers have attracted much attention due to their unique structure and properties. Polyaniline(PANI) nanocomposites have the advantages of simple preparation process, low cost, low toxicity, easy functionalization, etc., and have made great progress in tumor treatment. PANI nanocomposites prepared by modifying different functional compounds have greatly broadened the field of tumor treatment. Based on PANI nanocomposites, this article reviews their research progress in photothermal therapy, collaborative therapy, multimodal imaging guided therapy, and intelligent response therapy in the field of cancer diagnosis and treatment, and analyzes its development trends. |
| Key words: polyaniline(PANI) nanocomposite photothermal therapy synergy therapy multimodal imaging intelligent response |
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