| 摘要: |
| 磷酸钙是人体骨组织无机质的主要成分,而硅（Si）元素被证明具有诱导成骨的作用.因此,含Si的磷酸钙作为骨缺损修复材料受到了广泛的研究.以四水合硝酸钙（Ca（NO3）2·4H2O）、磷酸氢二铵（（NH4）2HPO4）和正硅酸乙酯（TEOS）分别为钙（Ca）源、磷（P）源和Si源,以十六烷基三甲基溴化铵（CTAB）为表面活性剂,采用水热法合成纳米硅-磷灰石粉体.研究了水热反应中CTAB添加量对合成的纳米硅-磷灰石粉体的化学组成、晶体结构和形貌的影响.结果表明：CTAB的加入不仅能降低纳米硅-磷灰石的颗粒尺寸,还能促进Si进入磷灰石晶格,提高硅-磷灰石中Si的含量.当CTAB添加量为0.55 g时,合成的硅-磷灰石的物质的量之比n（Ca）∶n（P）∶n（Si）可达5∶2∶1,此纳米硅-磷灰石粉体经高温煅烧后,更易于形成正交结构的硅磷酸钙（Ca5（PO4）2SiO4,CPS）相. |
| 关键词: 硅磷酸钙（CPS） 十六烷基三甲基溴化铵（CTAB） 表面活性剂 水热合成 |
| DOI：10.3969/J.ISSN.1000-5137.2023.01.002 |
| 分类号:O611.6 |
| 基金项目:上海市自然科学基金（21ZR1437000） |
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| Influence of CTAB addition on the composition and morphology of Si-apatite |
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JIN Ying, DENG Fanyan, NING Congqin
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College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China
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| Abstract: |
| Calcium phosphate is the main component of inorganic matter in human bone tissue, and silicon（Si） has been proved to have an effect on inducing bone formation. Therefore, silicon-containing calcium phosphate has been widely studied as a bone defect repair material. In this paper, nano Si-apatite powder was synthesized by a hydrothermal method, using calcium nitrate tetrahydrate（Ca（NO3）2·4H2O）, ammonium phosphate dibasic（（NH4）2HPO4）, and tetraethyl orthosilicate（TEOS） as calcium（Ca） source, phosphorus（P） source, and silicon source, respectively. In addition, cetyltrimethylammonium bromide（CTAB） was used as a surfactant and the effect of CTAB amount on the chemical composition, crystal structure, and morphology of the synthesized Si-apatite powder was studied. The results indicated that the addition of CTAB could not only reduce the particle size of nano Si-apatite, but also promote Si element entering the apatite lattice, improving the Si content in Si-apatite. When the addition amount of CTAB is 0.55 g, the mole ratio of n（Ca）∶n（P）∶n（Si） in the synthesized Si-apatite could reach 5∶2∶1. After calcination at high temperature, this nano Si-apatite powder was easier to form the orthogonal silicon-calcium phosphate（Ca5（PO4）2SiO4, CPS） phase. |
| Key words: silicon-calcium phosphate（CPS） cetyltrimethylammonium bromide（CTAB） surfactant hydrothermal synthesis |
