| 摘要: |
| 光热疗法（PTT）在癌症治疗领域是一种非常有前途的治疗方法.综述了近红外（NIR）光活化金纳米棒（Au NRs）在光热协同治疗肿瘤方面的最新进展.介绍了其在近红外一区（NIR-I）和近红外二区（NIR-Ⅱ）的光热潜力，及其在NIR-Ⅱ的窗口协同化学疗法（CT）、光动力学疗法（PDT）、化学动力学疗法（CDT）在对癌症的多模式治疗中的应用.此外，还讨论了该领域存在的挑战，为开发新型的NIR-Ⅱ光热剂提供了思路. |
| 关键词: 金纳米棒(Au NRs) 光热疗法(PTT) 近红外一区(NIR-I) 近红外二区(NIR-Ⅱ) |
| DOI：10.3969/J.ISSN.1000-5137.2022.05.010 |
| 分类号:O614.123 |
| 基金项目: |
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| Research progress of gold nanorods in photothermal therapy of NIR-Ⅱ window |
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ZHU Zixuan1, TIAN Qiwei1,2, YANG Shiping1
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1.College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China;2.Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China
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| Abstract: |
| Photothermal therapy(PTT) is a promising treatment in the field of cancer treatment. In this paper, we review the recent progress of near-infrared(NIR) photoactivated gold nanorods(Au NRs) in PTT of tumors. The photothermal potentials of near infrared-I(NIR-I) and near infrared-Ⅱ(NIR-Ⅱ) and their applications in NIR-Ⅱ window cooperative chemotherapy(CT), photodynamic therapy(PDT), chemodynamic therapy(CDT) and multi-mode treatment of cancer are reviewed. In addition, we also discuss the challenges in this field, which provides ideas for the development of novel NIR-Ⅱ photothermal agents. |
| Key words: gold nanorods(Au NRs) photothermal therapy(PTT) near infrared-I(NIR-I) near infrared-Ⅱ(NIR-Ⅱ) |
