| 摘要: |
| 近年来，铁基磁共振造影剂因其优良的磁学特性和良好的生物相容性，在医学成像领域中得到广泛关注。通过对铁基磁共振造影剂进行配体修饰，可以赋予其特异性靶向功能，从而显著提高对特定组织或病变的成像精度。这种靶向功能的提升不仅优化了成像质量，还增强了对病变的早期检测和准确诊断能力。结合多模态成像技术，铁基造影剂可以与CT、PET等成像手段互补，提供更为全面和精准的病理信息，为临床提供了更丰富的诊断依据。同时，成像引导治疗作为一种前沿技术，通过实时监测和反馈，进一步提高了治疗的精确性和效果。本综述将总结铁基磁共振造影剂的最新研究进展，探讨其在靶向成像、多模态融合以及成像引导治疗中的应用前景，并展望未来的发展方向。 |
| 关键词: 铁基磁共振造影剂 磁共振成像（MRI） 肿瘤治疗 多模态成像 |
| DOI： |
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| 基金项目:国家自然科学基金项目（面上项目，重点项目，重大项目） |
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| Progress in studying iron-based magnetic resonance contrast agents |
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guozepei
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Shanghai Normal University
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| Abstract: |
| In recent years, iron-based magnetic resonance contrast agents have garnered widespread attention in the medical imaging field due to their excellent magnetic properties and good biocompatibility. By modifying iron-based contrast agents with ligands, specific targeting functions can be endowed, significantly enhancing the imaging precision for specific tissues or lesions. This improvement in targeting capability not only optimizes image quality but also enhances the early detection and accurate diagnosis of lesions. Combined with multimodal imaging techniques, iron-based contrast agents can complement imaging methods such as CT and PET, providing more comprehensive and precise pathological information, offering a richer basis for clinical diagnosis. Additionally, image-guided therapy, as a cutting-edge technology, further improves the precision and effectiveness of treatment through real-time monitoring and feedback. This review will summarize the latest research progress of iron-based contrast agents, explore their application prospects in targeted imaging, multimodal fusion, and image-guided therapy, and look forward to future development directions. |
| Key words: iron-based contrast agent magnetic resonance imaging (MRI) tumor therapy multi-modal imaging |
