| 摘要: |
| 以马来海松酸与苯胺或其衍生物为原料,在聚乙二醇600(PEG-600)作为溶剂、甲苯作为带水剂的条件下,采用一步法合成了8个N-取代马来海松酸酰亚胺化合物;对化合物的结构进行了确认,并进行了初步的抗菌活性研究. |
| 关键词: 马来海松酸 苯胺或其衍生物 有机合成 抗菌活性 |
| DOI： |
| 分类号: |
| 基金项目:上海市科技人才计划项目(14R21421700) |
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| Synthesis and antibacterial activities of N-substituted maleopimarimide |
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LI Hui1, WANG Yin1, DAI Li1, LIAO Benren1, YANG Xushi1, WU Jie2, JIE Yuanping1
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1.Fine Chemistry R&D Institute,Technology Research Institute of Shanghai Huayi Group;2.Department of Chemistry,Fudan University
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| Abstract: |
| With Macrogol 600(PEG-600) as solvent and toluene as dehydrant,eight N-Substituted maleopimarimide compounds were synthesized from maleopimaric acid and aniline or its derivatives by one-step reaction;Their structures were confirmed and the antimicrobial activities of these compounds were also preliminarily investigated. |
| Key words: maleopimaric acid aniline or its derivatives organic synthesis antimicrobial activity |
